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Our microbiome -THe wonderful powerful microbes that we host
Antibiotics as Major Disruptors of Gut Microbiota
It is now understood that the gut microbiota is vital for normal development and functioning of the human body, especially for the priming and maturation of the adaptive immune system
Suppression of the gut microbiome ameliorates age-related arterial dysfunction and oxidative stress in mice
The results of the present study provide the first proof-of-concept evidence that the gut microbiome is an important mediator of age-related arterial dysfunction and therefore may be a promising therapeutic target for preserving arterial function with ageing, thereby reducing the risk of cardiovascular diseases.
Prebiotics Modulate the Effects of Antibiotics on Gut Microbial Diversity and Functioning in Vitro
There is therefore potential for using supplements to lessen the adverse effects of antibiotics. Further knowledge of such mechanisms could lead to better therapeutic manipulation of the human gut microbiota.
The Influence of the Gut Microbiome on Obesity in Adults and the Role of Probiotics, Prebiotics, and Synbiotics for Weight Loss
"In addition, studies have shown that supplementation with probiotics, prebiotics, and synbiotics may alter the secretion of hormones, neurotransmitters, and inflammatory factors, thus preventing food intake triggers that lead to weight gain."
Dietary fiber and prebiotics and the gastrointestinal microbiota
Technological and computational advances over the past decade have allowed researchers to gain a better understanding of the composition and function of the trillions of microbes that reside in the gastrointestinal tract, and there is mounting evidence of an interrelationship of diet, the gastrointestinal microbiota, and human health.
The Gut Microbiome and Its Role in Obesity
This fact raises the attractive possibility that manipulating the gut microbiota could facilitate weight loss or prevent obesity in humans. Emerging as possible strategies for obesity prevention and/or treatment are targeting the microbiota, in order to restore or modulate its composition through the consumption of live bacteria (probiotics), nondigestible or limited digestible food constituents such as oligosaccharides (prebiotics), or both (synbiotics), or even fecal transplants.
The gut microbiome in obesity
Among the risk factors contributing to obesity, human gut microbiome recently emerges with unprecedented intimacy in host metabolism and inflammation. With the advances in sequencing technology, more and more detailed understandings towards the intricate relationships linking gut microbiome and obesity have been continuously disclosed.
A healthy gastrointestinal microbiome is dependent on dietary diversity
Additional research into expanding gut microbial richness by dietary diversity is likely to expand concepts in healthy nutrition, stimulate discovery of new diagnostics, and open up novel therapeutic possibilities.
Human Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice
"However, this research provides clues into the role that the gut microbiota plays in neural changes that are associated with ASD. It suggests that ASD symptoms may one day be remedied with bacterial metabolites or a probiotic drug. Further, it opens the possibility that ASD, and perhaps other classical neurologic conditions, may be treated by therapies that target the gut rather than the brain, a seemingly more tractable approach."
The gut microbiome influences host diet selection behavior
"Together, these results demonstrate that gut microbiome can influence host diet selection behavior, perhaps by mediating the availability of essential amino acids, thereby revealing a mechanism by which the gut microbiota can influence host foraging behavior."
Prebiotic effect of dietary polyphenols: A systematic review
"...the consumption of polyphenols, especially catechins, anthocyanins and proanthocyanidins, increases the abundance of Lactobacillus, Bifidobacterium, Akkermansia, Roseburia, and Faecalibacterium spp. Moreover, polyphenols supplementation increased the production of short-chain fatty acids (SCFA), including butyrate.
A Microbiome Foundation for the Study of Crohn’s Disease
"Although we did not arrive at a single silver-bullet microbe that can point to a cure for CD, our work identified a clear list of potential culprits that may be involved in the initiation and/or progression of CD."
The Gut Microbiome in Psoriasis and Crohn’s Disease: Is Its Perturbation a Common Denominator for Their Pathogenesis?
However, if these diseases are mediated by an altered gut microbiota composition, its modulation and its communication with the host’s regional and systemic immune system represent an important opportunity to improve their outcome
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